Poe 2 Nonstop turn off my second monitor

I have problems with the second monitor only in poe 2 I don't know how to fix this problem, I tried to put different monitor resolution, also tried reinstalling the new nvidia driver that recently appeared. What is important, for about the first 8 hours of the game I was fine, but after that this problem happened.
GTX Super 1660
Ryzen 7 5700x

Bump as I'm having the same problem. I have to turn off my second monitor when playing as the constant off and on is too annoying and I'm worried it will damage the monitor.

My main monitor has a native resolution of 2560x1440 and is an LG UltraGear 27in QHD Nano IPS 165Hz G-Sync Gaming Monitor (27GP83B-B) and is only 2 years old.

My second monitor that is having the issue has a native resolution of 1920x1080 and is a LENOVO L24M-40 23.8" FHD IPS 4MS 100HZ FREESYNC MONITOR and is only 6 months old.

I also already enabled "Confine mouse to window" option to see if it fixes it, though I continue to have the issue both with and without this option on.

Bump. This is also happening to me to a T. Its annoying, and its only when I open PoE2, my monitors are fine doing literally anything else for hours. But the second I open PoE2....this issue happens.

PLEASE HELP