Complete Lockup on zoning.

My computer has completely locked up 5 times in the last two days when zoning. The mouse pointer is still active, but NOTHING else works. Windows key, Alt+F4, CTRL-ALT-DEL, nothing does anything. I have to hard boot my computer by holding down the power button and restarting.

Ref: 3,694,634,822

Edit: Adding times this happened again here:
7:45