Crashes Jiquani's Sanctum, Reliquary Vault

When I found my first reliquary key and wanted to open it, the game crashed on the vault loading screen. Happened again after restarting the game. So I had to wait for the instance to reset for me to be able to play the character again. Which obviously meant that I lost the key and any potential loot. For research purposes (not because I'm greedy and could not wait for this to be fixed) I sacrificed a second key I found, same thing.

I'm experiencing a similar crash during the campaign: Act 3, Jiquani's Sanctum. I can only move around for a few seconds before it crashes. When I try to load into the existing instance it crashes on the loading screen. Right now I cannot progress past this part in the campaign.

Apart from these crashes the game runs rather smoothly.

Here's my system specs if it's of any help:
-I'm playing on Windows 10 64bit
-Processor Intel(R) Core(TM) i7-9700K CPU @ 3.60GHz 3.60 GHz
-Installed RAM 16.0 GB
-Storage 1.82 TB HDD ST2000DM008-2FR102, 233 GB SSD Seagate BarraCuda
510 SSD ZP250CM30001
-Graphics Card NVIDIA GeForce RTX 2080 SUPER (8 GB)

Thanks for looking into it.
Last bumped on May 22, 2025, 1:21:16 PM
UPDATE:

The same crash as in Jiquani's Sanctum occurs when I open a "Vaal Factory" map containing a map boss encounter. Since it is the same boss as in said campaign area, that's what might be causing the crash.
Having the same problem with jiquanis sanctum a3.
Heres the important log part:

Spoiler
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2025/05/22 19:05:32 103320828 775aec31 [INFO Client 43496] [SCENE] Set Source [Jiquani's Machinarium]
2025/05/22 19:05:32 103320828 4228f822 [INFO Client 43496] [ENTITY] Wipe static entities
2025/05/22 19:05:32 103320906 99240e15 [DEBUG Client 43496] [SCENE] Height Map Texture: 630 x 1030
2025/05/22 19:05:32 103320984 4228f7e2 [INFO Client 43496] [ENTITY] Finalize static entities
2025/05/22 19:05:33 103321812 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321812 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321812 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #0
2025/05/22 19:05:33 103321812 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321812 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321812 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #1
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #2
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #3
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #4
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #5
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #6
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #7
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #8
2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : DecodeOneQuantum fail!

2025/05/22 19:05:33 103321828 d5a32738 [WARN Client 43496] OODLE ERROR : LZ corruption : OodleLZ_Decompress failed (2009830512 != 0)

2025/05/22 19:05:33 103321828 8a080687 [WARN Client 43496] Oodle failed to decompress. Retrying attempt #9
2025/05/22 19:05:33 103321828 8a0806eb [CRIT Client 43496] Oodle failed to decompress after 10 times. Aborting...
2025/05/22 19:05:33 103322343 93b1b552 [CRIT Client 43496] [RENDER] Shader uses incorrect vertex layout (shader: 0x00000218 mesh: 0x00000208)
Signature: "Metadata/EngineGraphs/base.fxgraph" "Metadata/EngineGraphs/GpuParticles/render_default.fxgraph" "Metadata/EngineGraphs/GpuParticles/Conversion/render_downscale.fxgraph" "Metadata/EngineGraphs/GpuParticles/Conversion/lock_mode.fxgraph" "Metadata/EngineGraphs/GpuParticles/Conversion/render_gravity.fxgraph" "Metadata/EngineGraphs/GpuParticles/Conversion/face_camera.fxgraph" "Metadata/EngineGraphs/GpuParticles/render_transform.fxgraph" "Metadata/EngineGraphs/GpuParticles/render_flip_normal.fxgraph" "Metadata/Effects/Graphs/General/BasicColour.fxgraph" "Metadata/Effects/Graphs/General/Ambient.fxgraph" "Metadata/Effects/Graphs/General/FlipbookOld.fxgraph" "Metadata/Effects/Graphs/General/DarkenTex.fxgraph"

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